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Journal of Zhejiang University SCIENCE B 1998 Vol.-1 No.-1 P.

http://doi.org/10.1631/jzus.B2300884


Energy deprivation-induced Autophagy and Aggrephagy: insights from yeast and mammals


Author(s):  Siyu FAN, Yingcong CHEN, Weijing YAO, Cong YI

Affiliation(s):  Department of Biochemistry, and Department of Hepatobiliary and Pancreatic Surgery of the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

Corresponding email(s):   yiconglab@zju.edu.cn

Key Words:  Autophagy, Glucose starvation, Solid aggrephagy, CCT2


Siyu FAN, Yingcong CHEN, Weijing YAO, Cong YI. Energy deprivation-induced Autophagy and Aggrephagy: insights from yeast and mammals[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .

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Abstract: 
autophagy plays a crucial role in maintaining cellular homeostasis in response to various stimuli. However, compared to research on nutrient deprivation-induced autophagy, the understanding of the molecular mechanisms and physiological/ pathological significance of autophagy triggered by energy deprivation remains limited. A primary focus of our lab is to elucidate how cells sense energy deprivation and initiate autophagy. Using the model organisms Saccharomyces cerevisiae and mammals, we have made a series of significant discoveries in this area. This review aims to provide a concise overview of these research findings.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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