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CLC number: R74
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Received: 2007-08-02
Revision Accepted: 2007-08-10
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Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment
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DIMITROV Borislav D., ATANASSOVA Penka A., RACHKOVA Mariana I.. Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment[J]. Journal of Zhejiang University Science B, 2007, 8(9): 609-611.
@article{title="Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment",
author="DIMITROV Borislav D., ATANASSOVA Penka A., RACHKOVA Mariana I.",
journal="Journal of Zhejiang University Science B",
volume="8",
number="9",
pages="609-611",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.B0609"
}
%0 Journal Article
%T Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment
%A DIMITROV Borislav D.
%A ATANASSOVA Penka A.
%A RACHKOVA Mariana I.
%J Journal of Zhejiang University SCIENCE B
%V 8
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%P 609-611
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0609
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T1 - Brain metastases of melanoma—mechanisms of attack on their defence system by engineered stem cells in the microenvironment
A1 - DIMITROV Borislav D.
A1 - ATANASSOVA Penka A.
A1 - RACHKOVA Mariana I.
J0 - Journal of Zhejiang University Science B
VL - 8
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SP - 609
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%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2007.B0609
Abstract: This report gives a better emphasis on the role of targeted effectors (e.g. a combination of 5-FC with CD-NSPCs as compared to the application of NSPCs alone) and how such delivery of pro-drug activating enzymes and other tumor-killing substances may overcome melanocytic defence system, interact with and promote the host defence and immune response modulations not only in melanoma but, potentially, in other highly-metastatic cancers.
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